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CRP 133 の 妊婦(フランス)

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報告タイトルをみるとわかってしまうので一番最後にリンク先。
フランス初の症例とのことです。

20代の妊婦さん。

妊婦や子どもの相談は感染症医だけでは対応が難しいことが多いので、別の領域の専門家ともすぐ相談。
相談できる知り合いやルートをもっておくことが大切。

"A primigravida woman in her mid-20s presented at 26 weeks of gestation in October 2012 with blurred vision, chills, headache, back pain and cough that had lasted two days."

非特異的・・・。

" Her previous medical history was unremarkable. Physical examination revealed a high body temperature (39.1 °C). The fetal heart rate was normal and there was no uterine contraction.
Antibiotics (ampicillin and gentamicin) were introduced systematically.
Two days later (four days after symptom onset, day 4), she was transferred to the regional reference hospital because of abnormalities in test results from blood and urine sampled at day 3 .

発症2日目のCRP(しーあーるぴー)が17、4日めは133。
調べたけど陰性: leptospirosis, toxoplasmosis, viral hepatitis, simplex viruses, cytomegalovirus, Epstein–Barr virus


産婦人科の先生診察おねがいします。

"Abdominal sonography showed no hepatobiliary pathology, but the presence of only one kidney. Obstetric examination and ultrasound were normal, with normal fetal growth. "

しかし7日目。

"The patient was closely monitored and antenatal prophylactic application of steroids (betamethasone, 12 mg per day for two days) for fetal pulmonary maturation was given. On day 7, the patient developed acute renal failure (creatininemia at 260 µmol/L) (norm: 53–115 µmol/L)"

赤ちゃんは?
緊急帝王切開(27週)で1095gでした。無事です。

"After the birth, the mother was immediately transferred to a nephrology intensive care unit. Liver enzymes, blood count and coagulation normalised first, then renal function increased and was within the normal ranges within three weeks (Table), without the need for dialysis."


さて答えは・・・下記をクリック。
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20464


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