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週に4-5日のART

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Short-Cycle Four-Day ARV Regimen for HIV Shows Efficacy in Maintaining Viral Suppression

第21回の国際エイズ会議(Durban, South Africa | July 18-22, 2016)http://www.aids2016.orgで次のような発表がありました。

平たくいうと維持療法ならば、週に4-5日間か、それ以下の日数でもウイルス抑制が可能かも・・という報告。

A maintenance regimen for HIV treatment that reduces the regimen of antiretroviral (ARV) therapy to 4 days a week demonstrates efficacy in sustaining viral suppression after 48 weeks.

With HIV patients facing lifelong therapy regimens, ongoing efforts are focusing on strategies for reducing long-term cumulative toxicity of anti-retroviral (ARV) drugs, and encouraging results have been shown in a previous study reducing treatment from 7 days per week to 5 days per week, and sometimes even 4 or less (Liebowitch J, et al. FASEB J. June 2015 29:2223-4).

編集長:地味ですが、患者さんの負担(経済的、副作用的、精神的)を考えると極めて重要。

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